Metastasis and AKT activation
Copyright policy )Metastasis and AKT activation
AbstractMetastasis, responsible for 90% of cancer patient deaths, is an inefficient process because many tumor cells die. The survival of metastatic tumor cells should be considered as a critical therapeutic target. This review provides a new perspective regarding the role of AKT in tumor survival, and the rationale to target AKT in anti‐metastasis therapies. J. Cell. Physiol. 218: 451–454, 2009. © 2008 Wiley‐Liss, Inc.
- Dana-Farber Cancer Institute United States
- Karmanos Cancer Institute United States
- Harvard University United States
- McLaren Health Care United States
- Wayne State University United States
Adherens Junctions, Protein Serine-Threonine Kinases, Models, Biological, 3-Phosphoinositide-Dependent Protein Kinases, Enzyme Activation, Neoplasms, Cell Adhesion, Animals, Humans, Snail Family Transcription Factors, Neoplasm Metastasis, Proto-Oncogene Proteins c-akt, Transcription Factors
Adherens Junctions, Protein Serine-Threonine Kinases, Models, Biological, 3-Phosphoinositide-Dependent Protein Kinases, Enzyme Activation, Neoplasms, Cell Adhesion, Animals, Humans, Snail Family Transcription Factors, Neoplasm Metastasis, Proto-Oncogene Proteins c-akt, Transcription Factors
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