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Journal of Clinical Laboratory Analysis
Article . 2007 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
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Improved method to calculate the antibody avidity index

Authors: C T, Perciani; P S, Peixoto; W O, Dias; F S, Kubrusly; M M, Tanizaki;

Improved method to calculate the antibody avidity index

Abstract

AbstractThe methods currently used to determine the immunoglobulin avidity index (AI) require the choice of a reference point in the ELISA titration curve. Since both curves, with and without denaturating reagents, seldom run in parallel, the AI value becomes highly dependent on this reference. The new method for AI calculation presented here takes into account the whole data of the ELISA titration curve in which the final numerical AI is the average of each point. J. Clin. Lab. Anal. 21:201–206, 2007. © 2007 Wiley‐Liss, Inc.

Keywords

Mice, Protein Denaturation, Animals, Newborn, Immunoglobulin G, Antibody Affinity, Thiosulfates, Animals, Reproducibility of Results, Enzyme-Linked Immunosorbent Assay

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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
46
Top 10%
Top 10%
Average
gold