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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Biomedica...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Journal of Biomedical Materials Research
Article . 1991 . Peer-reviewed
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Materials for enhancing cell adhesion by immobilization of cell‐adhesive peptide

Authors: Yukio Imanishi; Masako Kajihara; Yoshihiro Ito;

Materials for enhancing cell adhesion by immobilization of cell‐adhesive peptide

Abstract

AbstractMaterials to enhance cell adhesion were synthesized by surface integration of peptide, Arg‐Gly‐Asp‐Ser(RGDS), which is an active‐site sequence of cell‐adhesive proteins. Polystyrene film was glowdischarged and graft‐copolymerized with acrylic acid. Then the peptide was immobilized to the poly(acrylic acid) grafts by using water‐soluble carbodimide. The cell‐adhesive activity of the RGDS‐immobilized film increased with increasing amount of immobilized peptide, and approached the activity of fibronectin(FN)‐immobilized film. The RGDS‐immobilized film was more stable against heat treatment and pH variation than the FN‐immobilized film. In addition, the RGDS‐immobilized film enhanced cell growth more strongly than the FN‐immobilized film.

Related Organizations
Keywords

Mice, Molecular Sequence Data, Cell Adhesion, Temperature, Animals, Polystyrenes, Spectrophotometry, Ultraviolet, Amino Acid Sequence, Hydrogen-Ion Concentration, Peptides, Cell Division, Cells, Cultured, Fibronectins

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    135
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
135
Top 10%
Top 1%
Top 10%
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