Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals
Copyright policy )Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals
AbstractIt has been shown that the mammalian activating transcription factor 4 (ATF4) is involved in many different physiological events, such as eye development, stress response, learning, and memory. However, several recent studies have demonstrated that ATF4 also plays an important role in the regulation of lipid and glucose metabolism, energy homeostasis, insulin secretion, and sensitivity, suggesting that ATF4 is a master regulator of metabolism. This review summarizes the most recent progress in the understanding of the novel roles of ATF4 in the regulation of metabolism. © 2012 IUBMB IUBMB Life, 2012.
- Chinese Academy of Sciences China (People's Republic of)
- Shanghai Institutes for Biological Sciences China (People's Republic of)
Animals, Carbohydrate Metabolism, Homeostasis, Humans, Lipid Metabolism, Activating Transcription Factor 4
Animals, Carbohydrate Metabolism, Homeostasis, Humans, Lipid Metabolism, Activating Transcription Factor 4
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