Many routes to a micro RNA
Copyright policy )Many routes to a micro RNA
AbstractMicro RNAs (miRNAs) are ∼22 nt small RNAs that function as posttranscriptional negative regulators of gene expression. Thousands of these molecules have so far been identified across the metazoan and plant kingdoms. Although most miRNAs share the same biogenesis pathway, numerous noncanonical miRNAs and other small RNAs have also been identified. In this review, we will discuss these alternate small RNA biogenesis pathways as well as recent discoveries of non‐miRNA functions of the miRNA biogenesis machinery. This review will focus only on metazoan pathways. © 2011 IUBMB IUBMB Life, 63(11): 972–978, 2011
- University of Melbourne Australia
- Walter and Eliza Hall Institute of Medical Research Australia
Ribonuclease III, MicroRNAs, Gene Expression Regulation, Animals, Gene Expression, Humans, RNA Processing, Post-Transcriptional, RNA, Small Interfering
Ribonuclease III, MicroRNAs, Gene Expression Regulation, Animals, Gene Expression, Humans, RNA Processing, Post-Transcriptional, RNA, Small Interfering
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