Deciphering the roles of FOXO1 in human neoplasms

descriptionPublicationkeyboard_double_arrow_right Article 02 Mar 2018 English Publisher:WileyJournal:International Journal of Cancer, volume 143, pages 1,560-1,568 (issn: 0020-7136, eissn: 1097-0215,

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Authors: Shuai Jiang; Tian Li; Zhi Yang; Wei Hu; Yang Yang;

doi: 10.1002/ijc.31338

pmid: 29473160

Deciphering the roles of FOXO1 in human neoplasms

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Abstract

Neoplasms constituted an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This article may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms.

Related Organizations

Ministry of Education of the People's Republic of China
China (People's Republic of)
Northwest University
China (People's Republic of)
Air Force Medical University
China (People's Republic of)

Keywords

Forkhead Box Protein O1, Neoplasms, Humans

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