Baimantuoluolines D – F, Three New Withanolides from the Flower of Datura metel L.

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2008 English Publisher:WileyJournal:Helvetica Chimica Acta, volume 91, pages 964-971 (issn: 0018-019X, eissn: 1522-2675,

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Authors: Bingyou Yang; Qiuhong Wang; Yonggang Xia; Weisheng Feng; Haixue Kuang;

doi: 10.1002/hlca.200890103

Baimantuoluolines D – F, Three New Withanolides from the Flower of Datura metel L.

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Abstract

AbstractThree new withanolide compounds, named baimantuoluolines D–F, along with three known withanolides and a lignan were isolated from the flower of Datura metel L., the parts effective against psoriasis. The structures of the new compounds were elucidated as (5α,6β,12β,20R,22R,24R,25S)‐21,24‐epoxy‐5,6,12‐trihydroxy‐27‐methoxy‐1‐oxowith‐2‐enolide (1), (5α,6β,12β,20R,22R,24R,25S)‐21,24‐epoxy‐5,6,12,27‐tetrahydroxy‐1‐oxowith‐2‐enolide (2), and (5α,6β,12β,22R)‐5,6,12,21‐tetrahydroxy‐1‐oxowith‐24‐enolide(3) on the basis of physicochemical evidence.

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Heilongjiang University of Chinese Medicine
China (People's Republic of)

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