
LTP, the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDARs diffuse away upon LTP. Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP.
Biomedical and clinical sciences, Neuronal Plasticity, Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Biological Sciences, Autoimmune Disease, Medical and Health Sciences, Receptors, N-Methyl-D-Aspartate, Biological sciences, Information and Computing Sciences, Receptors, Synapses, Animals, N-Methyl-D-Aspartate, Developmental Biology
Biomedical and clinical sciences, Neuronal Plasticity, Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Biological Sciences, Autoimmune Disease, Medical and Health Sciences, Receptors, N-Methyl-D-Aspartate, Biological sciences, Information and Computing Sciences, Receptors, Synapses, Animals, N-Methyl-D-Aspartate, Developmental Biology
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