AbstractTwo complementary one‐pot, three component synthetic strategies based on copper(I)‐catalyzed azide–alkyne cycloadditions (CuAAC) have been developed, which allow the efficient assembly of glycosyl‐derived alkynes or azides with highly fluorescent boron–dipyrromethene (BODIPY) cores containing azido or alkyne moieties, respectively. The resulting carbohydrate–BODIPY derivatives display excellent photophysical and laser properties that relate to the spacer (amino group or aromatic ring) employed in each of the synthetic protocols.