Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates

descriptionPublicationkeyboard_double_arrow_right Article 13 Sep 2013 English Publisher:WileyJournal:European Journal of Organic Chemistry, volume 2,013, pages 7,095-7,100 (issn: 1434-193X, eissn: 1099-0690,

Copyright policy )

Authors: Javier Vicario; Pablo Ortiz; Francisco Palacios;

doi: 10.1002/ejoc.201300950

Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates

- Summary
- Metrics

Abstract

AbstractAn efficient method for the preparation of quaternary α‐aminophosphonic acid derivatives is reported. The nucleophilic addition of organometallic reagents to α‐ketiminophosphonates allows the preparation of quaternary α‐aminophosphonates. The diastereoselective synthesis of a quaternary α‐aminophosphonate using a chiral tartaric‐acid‐derived phosphonate is also described.

Related Organizations

University of the Basque Country
Spain

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	13
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average