ABSTRACTImpactful translational research requires new approaches to computational analysis and bioethics, both of which have been advanced by adoption of community‐engagement strategies. Community knowledge and experience will hone data collection, research, and insights and accelerate the impact of derived translational applications to improve individual health, medical decision‐making, and public health policy. In the context of translational research with big health data, meaningful community‐researcher engagement will require developing and deploying coengagement tools across the research life cycle and developing approaches for novel coproduction.