Targeted integration of genes in Xenopus tropicalis
Copyright policy )Targeted integration of genes in Xenopus tropicalis
AbstractWith the successful establishment of both targeted gene disruption and integration methods in the true diploid frog Xenopus tropicalis, this excellent vertebrate genetic model now is making a unique contribution to modelling human diseases. Here, we summarize our efforts on establishing homologous recombination‐mediated targeted integration in Xenopus tropicalis, the usefulness, and limitation of targeted integration via the homology‐independent strategy, and future directions on how to further improve targeted gene integration in Xenopus tropicalis.
- University of Copenhagen Denmark
- Southern University of Science and Technology China (People's Republic of)
- University of Copenhagen Denmark
Animal, Xenopus, Gene Expression Regulation, Developmental, Review, Xenopus Proteins, Disease Models, Animal, Gene Expression Regulation, Disease Models, Gene Targeting, Journal Article, Animals, Humans, Developmental
Animal, Xenopus, Gene Expression Regulation, Developmental, Review, Xenopus Proteins, Disease Models, Animal, Gene Expression Regulation, Disease Models, Gene Targeting, Journal Article, Animals, Humans, Developmental
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