Real‐world data in the molecular era—finding the reality in the real world

descriptionPublicationkeyboard_double_arrow_right Article 12 Jan 2016 English Publisher:WileyJournal:Clinical Pharmacology & Therapeutics, volume 99, pages 186-197 (issn: 0009-9236, eissn: 1532-6535,

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Authors: D J, Dickson; J D, Pfeifer;

doi: 10.1002/cpt.300

pmid: 26565654

Real‐world data in the molecular era—finding the reality in the real world

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Abstract

Real‐world data (RWD) promises to provide a pivotal element to the understanding of personalized medicine. However, without true representation (or the reality) of the patient‐disease biosystem and its molecular contributors, RWD may hamper rather than help this advancement. In this review article, we discuss RWD vs. clinical reality and the disconnects that exist currently (emphasizing molecular medicine), and methods of closing the gaps between RWD and reality.

Related Organizations

University of Mary
United States
Washington University in St. Louis
United States

Keywords

Pharmacogenetics, Databases, Genetic, High-Throughput Nucleotide Sequencing, Humans, Molecular Medicine, Precision Medicine

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