Medicinal chemistry of cannabinoids
Copyright policy )Medicinal chemistry of cannabinoids
The endocannabinoid system comprises the two well characterized Gi/o‐protein coupled receptors (cannabinoid receptor 1 (CB1) and CB2), their endogenous lipid ligands, and the enzymes involved in their biosynthesis and biotransformation. Drug discovery efforts relating to the endocannabinoid system have been focused mainly on the two cannabinoid receptors and the two endocannabinoid deactivating enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL). This review provides an overview of cannabinergic agents used in drug research and those being explored clinically.
- King’s University United States
- Northeastern University United States
- Northwestern University United States
- University of Massachusetts System United States
- King Abdulaziz University Saudi Arabia
Translation, Cannabinoids, Chemistry, Pharmaceutical, Monoacylglycerol Lipases, Amidohydrolases, Receptor, Cannabinoid, CB2, Receptor, Cannabinoid, CB1, Drug Discovery, Humans
Translation, Cannabinoids, Chemistry, Pharmaceutical, Monoacylglycerol Lipases, Amidohydrolases, Receptor, Cannabinoid, CB2, Receptor, Cannabinoid, CB1, Drug Discovery, Humans
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