AbstractThe central nucleus of the inferior colliculus in the cat is distinguished by its unique neuropil. In Golgi‐impregnated material, it is composed primarily of neurons with disc‐shaped dendritic fields arranged into parallel arrays, or laminae, complemented by the laminar afferent axons from the lateral lemniscus. Large, medium‐large, medium, and small varieties of disc‐shaped cells are distinguished on the basis of the size of the dendritic field and cell body size, dendritic diameter, and dendritic appendages. A second major class of neurons in the central nucleus are the stellate cells with dichotomously branched, spherical‐shaped dendritic trees. Simple, complex, and small stellate cells can be distinguished by their size and by the complexity of the dendritic and axonal branching. Laminar afferent axons are recognized by the nests of collateral side branches and the grapelike clusters of terminal boutons – thick, thin, and intermediate‐sized varieties are apparent. Other axon types include local collaterals of central nucleus neurons, some of which are distinguished by their frequent and complex collaterals.In the central nucleus, the configuration of the fibrodendritic laminae, the presence of subdivisions, and the banding of afferent axons suggest levels of organization which are superimposed on the synaptic arrangements of the individual cell and axon types. The laminar pattern, as studied in serial Golgi‐impregnated sections, differs from previous reports. The central nucleus contains subdivisions which can be distinguished by their laminar pattern, different proportions of cell types, and the packing density of the cell bodies and axonal plexus.The patterns of degeneration observed in Nauta‐stained material after lesions of caudal auditory pathways show that thick and fine afferent fibers form dense bands of degeneration separated by sparse, fine‐fiber degeneration. The bands are thicker than individual laminae but smaller than the subdivisions.The intrinsic organization of the neurons and axons, combined with the laminar organization, subdivisions, and banding patterns, each may contribute different aspects to the processing of auditory information in the central nucleus.