Multitarget Drug Discovery and Polypharmacology

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 09 Apr 2016 Italy English Publisher:WileyJournal:ChemMedChem, volume 11, pages 1,190-1,192 (issn: 1860-7179, eissn: 1860-7187,

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Authors: BOLOGNESI, MARIA LAURA; CAVALLI, ANDREA;

doi: 10.1002/cmdc.201600161

pmid: 27061625

handle: 11585/588050

Multitarget Drug Discovery and Polypharmacology

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Abstract

Promising promiscuity: Guest editors Maria Laura Bolognesi and Andrea Cavalli set the stage for this ChemMedChem Special Issue on Polypharmacology and Multitarget Drugs. They highlight cases in which a departure from the "one target, one drug" paradigm has proven advantageous, with single molecules that can engage two or more targets to address a given pathology. Articles in this issue underscore the importance of focusing ever more attention to polypharmacology in drug discovery efforts.

Country

Italy

Related Organizations

Alma Mater Studiorum University of Bologna
Italy
Italian Institute of Technology
Italy

Keywords

Epigenomics, Alzheimer Disease, Polypharmacology, Anti-Inflammatory Agents, Humans, Antineoplastic Agents, Alzheimer Disease; Anti-Inflammatory Agents; Antineoplastic Agents; Communicable Diseases; Epigenomics; Humans; Polypharmacology; Pharmacology, Toxicology and Pharmaceutics (all); Organic Chemistry; Molecular Medicine, Communicable Diseases

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