
ABSTRACTRanolazine utilization in the management of refractory angina has been established by multiple randomized clinical studies. However, there is growing evidence showing an evolving role in the field of cardiac arrhythmias. Multiple experimental and clinical studies have evaluated the role of ranolazine in prevention and management of atrial fibrillation, with ongoing studies on its role in ventricular arrhythmias. In this review, we will discuss the pharmacological, experimental, and clinical evidence behind ranolazine use in the management of various cardiac arrhythmias.
Action Potentials, Arrhythmias, Cardiac, Sodium Channels, Kinetics, Treatment Outcome, Heart Conduction System, Heart Rate, Ranolazine, Animals, Humans, Anti-Arrhythmia Agents, Sodium Channel Blockers
Action Potentials, Arrhythmias, Cardiac, Sodium Channels, Kinetics, Treatment Outcome, Heart Conduction System, Heart Rate, Ranolazine, Animals, Humans, Anti-Arrhythmia Agents, Sodium Channel Blockers
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