descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2010 English Publisher:WileyJournal:Clinical Cardiology, volume 33 (issn: 0160-9289, eissn: 1932-8737,

Authors: Henry J. Dargie; Charles Angus Murphy; Robin A.P. Weir; Colin J. Petrie;

doi: 10.1002/clc.20631

pmid: 20043328

pmc: PMC6653233

Drink, Drugs, and the QT Interval

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Abstract

AbstractThe effects of several prescription and illicitly‐used drugs on electrocardiographic repolarization are well documented, most frequently manifested as prolongation of the corrected QT (QTc) interval. The combination of multiple repolarization‐modulating drugs taken in high dosage can occasionally lead to extreme abnormalities of the QTc interval and ST‐segment on the surface ECG, which can lead to the erroneous diagnosis of underlying myocardial ischemia and inappropriate treatment. We report on one such case in which the acute management of a syncopal patient was detrimentally influenced by misinterpretation of a very unusual ECG. Copyright © 2010 Wiley Periodicals, Inc.

Related Organizations

NHS Greater Glasgow and Clyde
United Kingdom
Western Infirmary
United Kingdom

Keywords

Adult, Time Factors, Alcohol Drinking, Substance-Related Disorders, Myocardial Ischemia, Arrhythmias, Cardiac, Unnecessary Procedures, Syncope, Electrocardiography, Heart Conduction System, Humans, Female, Diagnostic Errors

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