
doi: 10.1002/chir.20050
pmid: 15239073
Tiropramide is an antispasmodic drug that has a chiral center. Resolution of tiropramide enantiomers on various kinds of chiral stationary phases was performed by HPLC. A good resolution on a leucine-derived chiral stationary phase was found. An improved chromatographic condition to resolve racemic tiropramide on the CSP was examined by changing the flow rate, composition, and kind of mobile phases.
Parasympatholytics, Tyrosine, Stereoisomerism, Chromatography, High Pressure Liquid
Parasympatholytics, Tyrosine, Stereoisomerism, Chromatography, High Pressure Liquid
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