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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Chemischer Informati...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Chemischer Informationsdienst
Article . 1979 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Journal of Medicinal Chemistry
Article . 1979 . Peer-reviewed
Data sources: Crossref
ChemInform
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ChemInform Abstract: ANALOGUES OF METHOTREXATE

Authors: Carroll Temple; Robert D. Elliott; Y. F. Shealy; John A. Montgomery; James R. Piper; Eugene C. Roberts;

ChemInform Abstract: ANALOGUES OF METHOTREXATE

Abstract

AbstractÜber eine Alkylierung mit 6‐(Brommethyl)‐2,4‐pteridindiamin und Analoge und (teilweise) Verseifung werden die Verbindungen (II) bis (V) in Ausbeuten bis zu 97% dargestellt.

Keywords

Cell Survival, Antineoplastic Agents, In Vitro Techniques, Mice, Structure-Activity Relationship, Methotrexate, Liver, Carcinoma, Squamous Cell, Animals, Folic Acid Antagonists, Humans, Columbidae, Leukemia L1210

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    46
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
46
Average
Top 10%
Top 10%
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