Loss of TSC1 in secondary angiosarcoma of the breast
Copyright policy )Loss of TSC1 in secondary angiosarcoma of the breast
Key Clinical MessagePost‐radiation angiosarcoma of the breast is a rare complication associated with a poor prognosis. This case reports the first loss of function mutation in TSC1 in breast radiation‐induced angiosarcoma and illustrates the utility of evaluating these markers to identify potential therapeutic targets.AbstractPost‐radiation angiosarcoma of the breast is rare and associated with a poor prognosis. This case presents the first loss of function mutation in TSC1 in breast radiation‐induced angiosarcoma. Evaluation of these markers can aid in identifying potential therapeutic targets.
- The Ohio State University Wexner Medical Center United States
mTOR inhibitors, Medicine (General), R, radiation‐induced angiosarcoma, Case Report, radiation, breast cancer, R5-920, TSC1 mutation, Medicine, nab‐sirolimus
mTOR inhibitors, Medicine (General), R, radiation‐induced angiosarcoma, Case Report, radiation, breast cancer, R5-920, TSC1 mutation, Medicine, nab‐sirolimus
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