Are de novo rea(21;21) chromosomes really de novo?

descriptionPublicationkeyboard_double_arrow_right Article 26 Aug 2015 English Publisher:WileyJournal:Clinical Case Reports, volume 3, pages 786-789 (issn: 2050-0904, eissn: 2050-0904,

Copyright policy )

Authors: Hervé, Bérénice; Quibel, Thibaud; Taieb, Stéphane; Ruiz, Mireille; Molina-Gomes, Denise; Vialard, François;

doi: 10.1002/ccr3.341

pmid: 26509006

pmc: PMC4614639

Are de novo rea(21;21) chromosomes really de novo?

- Summary
- Subjects
- Metrics

Abstract

Key Clinical MessageWe report a rare case of recurrent trisomy 21 caused by an isochromosome 21q and what is very likely to be maternal germ‐line cell mosaicism. Over 90% of cases of rob(21;21) reported in the literature are due to an isochromosome 21q, with a risk of recurrence of more than 10%.

Related Organizations

Centre Hospitalier Intercommunal de Poissy
France

Keywords

Case Reports

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	35
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%