The biological characteristics of the canine adenovirus type 1 from fox and the transcriptome analysis of the infected MDCK cell
Copyright policy )The biological characteristics of the canine adenovirus type 1 from fox and the transcriptome analysis of the infected MDCK cell
AbstractCanine adenovirus type 1 (CAdV‐1) is the etiologic agent of fox encephalitis, and a virus strain from fox encephalitis is isolated and related research are conducted. In this experiment, the results showed that the F1301 strain was confirmed to be the CAdV‐1. The whole genome of the CAdV‐1 F1301 strain isolated from fox was 30,535 bp and had higher homology to the other reported CAdV‐1 strains. After 0, 12, and 36 h of CAdV‐1 infection, the difference gene of the 592 long noncoding RNA and 11,215 microRNA were involved in cell responses to CAdV‐1 infection through the PI3K‐AKT, Wnt, Herpes simplex, hepatitis C, and Epstein–Barr virus infection pathway in Madin–Darby canine kidney cell line (MDCK). The results indicate that the biological characterization of the CAdV‐1 and the MDCK cell‐CAdV‐1 interaction are clarified.
- Institute of Special Animal and Plant Sciences China (People's Republic of)
- Chinese Academy of Agricultural Sciences China (People's Republic of)
- Institute of Animal Sciences China (People's Republic of)
- Lanzhou Veterinary Research Institute China (People's Republic of)
- Huazhong Agricultural University China (People's Republic of)
Dogs, Gene Expression Regulation, Gene Expression Profiling, Animals, Foxes, Gene Expression, Adenoviruses, Canine, Transcriptome, Madin Darby Canine Kidney Cells
Dogs, Gene Expression Regulation, Gene Expression Profiling, Animals, Foxes, Gene Expression, Adenoviruses, Canine, Transcriptome, Madin Darby Canine Kidney Cells
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).7 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!