Six‐Colour HyBeacon Probes for Multiplex Genetic Analysis

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 24 Nov 2010 United Kingdom English Publisher:WileyJournal:ChemBioChem, volume 11, pages 2,530-2,533 (issn: 1439-4227, eissn: 1439-7633,

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Authors: Richardson, James A.; Gerowska, Marta; Shelbourne, Montserrat; French, David; Brown, Tom;

doi: 10.1002/cbic.201000623

pmid: 21108272

Six‐Colour HyBeacon Probes for Multiplex Genetic Analysis

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Abstract

A combination of six HyBeacon probes has been used in multiplex genetic analysis to analyse mutations in the CFTR gene of PCR-amplified human DNA. Multicolour HyBeacons of this type have great potential in human genetic screening and point-of-care diagnosis. © 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.

Country

United Kingdom

Related Organizations

University of Oxford
United Kingdom
University of Southampton
United Kingdom

Keywords

Base Sequence, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, Point Mutation, Genetic Testing, Oligonucleotide Probes, Polymerase Chain Reaction, Fluorescent Dyes

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