Production of Aniline Derivatives from Cladosporium cladosporioides TFU‐13 and Volutella sp. TFU‐28 in the Presence of SAHA
Copyright policy )Production of Aniline Derivatives from Cladosporium cladosporioides TFU‐13 and Volutella sp. TFU‐28 in the Presence of SAHA
ABSTRACTBiotransformation of suberoylanilide hydroxamic acid (SAHA) by soil‐derived Cladosporium cladosporioides TFU‐13 and Volutella sp. TFU‐28 yielded a panel of aniline derivatives, including two new metabolites (1 and 4) and six previously reported compounds. Structural elucidation of the novel metabolites was conducted using comprehensive nuclear magnetic resonance (NMR) and high‐resolution mass spectrometric analyses. Among these, 2‐acetamidophenol (6) displayed antioxidant activity, as indicated by diphenylpicrylhydrazyl (DPPH) radical scavenging assays.
- Tianjin Institute of Industrial Biotechnology China (People's Republic of)
- Jiangxi Science and Technology Normal University China (People's Republic of)
- Tianjin University of Traditional Chinese Medicine China (People's Republic of)
- Nanchang Normal University China (People's Republic of)
- Chinese Academy of Sciences China (People's Republic of)
Vorinostat, Aniline Compounds, Magnetic Resonance Spectroscopy, Molecular Structure, Picrates, Biphenyl Compounds, Hydroxamic Acids, Cladosporium, Antioxidants, Biotransformation
Vorinostat, Aniline Compounds, Magnetic Resonance Spectroscopy, Molecular Structure, Picrates, Biphenyl Compounds, Hydroxamic Acids, Cladosporium, Antioxidants, Biotransformation
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