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Cancer Medicine
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Cancer Medicine
Article . 2020
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Article . 2019
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Cancer Medicine
Article . 2019
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Prognostic nomograms to predict overall survival and cancer‐specific survival in patients with pelvic chondrosarcoma

Authors: Li Chen; Cheng Long; Jiaxin Liu; Xin Duan; Zhou Xiang;

Prognostic nomograms to predict overall survival and cancer‐specific survival in patients with pelvic chondrosarcoma

Abstract

AbstractBackgroundThe pelvis is the most common site of chondrosarcoma (CS), and the prognosis for patients with pelvic CS is worse than that for patients with CS in the extremities. However, clinicians have had few tools for estimating the likelihood of survival in patients with pelvic CS. Our aim was to develop nomograms to predict survival of patients with pelvic CS.MethodsData from the Surveillance, Epidemiology, and End Results (SEER) database of patients with pelvic CS between 2004 and 2016 were retrieved for retrospective analysis. Univariate and multivariate Cox analyses were used to identify independent prognostic factors. On the basis of the results of the multivariate analyses, nomograms were constructed to predict the likelihood of 3‐ and 5‐year overall survival (OS) and cancer‐specific survival (CSS) of patients with pelvic CS. The concordance index (C‐index) and calibration curves were used to test the models.ResultsIn univariate and multivariate analyses of OS, sex, pathologic grade, tumor size, tumor stage, and surgery were identified as the independent risk factors. In univariate and multivariate analyses of CSS, pathologic grade, tumor size, tumor stage, and surgery were identified as the independent risk factors. These characteristics except surgery were integrated in the nomograms for predicting 3‐ and 5‐year OS and CSS, and the C‐indexes were 0.758 and 0.786, respectively.ConclusionThe nomograms precisely and individually predict OS and CSS of patients with pelvic CS and could aid in personalized prognostic evaluation and individualized clinical decision‐making.

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Keywords

Adult, Male, Adolescent, overall survival, Clinical Decision-Making, Chondrosarcoma, Bone Neoplasms, pelvis, Kaplan-Meier Estimate, nomogram, cancer‐specific survival, Risk Factors, Humans, Precision Medicine, Child, Pelvic Bones, RC254-282, Aged, Retrospective Studies, Aged, 80 and over, chondrosarcoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Clinical Cancer Research, Middle Aged, Prognosis, SEER, Nomograms, Female, SEER Program

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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Top 10%
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