Mass spectrometric identification of abnormal aromatic compounds in the urine of a child with Reye's like syndrome

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1984 English Publisher:WileyJournal:Biological Mass Spectrometry, volume 11, pages 127-131 (issn: 0306-042X, eissn: 1096-9888,

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Authors: F, Rocchiccioli; P H, Cartier; P F, Bougnères;

doi: 10.1002/bms.1200110307

pmid: 6722284

Mass spectrometric identification of abnormal aromatic compounds in the urine of a child with Reye's like syndrome

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Abstract

The urine of a young child with hypoglycemia and a Reye's like syndrome contained an excess of unusual aromatic products with a three carbon chain, phenylpropionylglycine and 3- and 4-(hydroxyphenyl)propionic and 3-(3-methoxy-4-hydroxyphenyl)propionic acids, as well as of organic acids usually found in fatty acid beta-oxidation defects: the mono- and dicarboxylic acids derived from the respective (omega-1) and omega-oxidation of C6 to C10 fatty acids.

Related Organizations

Hôpital Saint-Vincent-de-Paul
France
French Institute of Health and Medical Research
France

Keywords

Male, Phenylpropionates, Reye Syndrome, Fatty Acids, Humans, Infant, Oxidation-Reduction, Gas Chromatography-Mass Spectrometry

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