
doi: 10.1002/bmc.844
pmid: 17474074
AbstractOver the last decade, time‐of‐flight (TOF) instruments have increasingly been used as quantitation tools. In addition, because of their high resolving power, they can be used for verification of empirical formulas. Historically, TOF instruments have had limited quantitation capabilities because of their narrow dynamic range. However, recent advances have improved these limitations. This review covers the rationale for using TOF for LC detection, and describes the many methods currently in the literature for the quantitation of pharmaceuticals, environmental pollutants, explosives and many phytochemicals. Copyright © 2007 John Wiley & Sons, Ltd.
Spectrometry, Mass, Electrospray Ionization, Explosive Agents, Proteome, Plant Extracts, Pesticide Residues, Reproducibility of Results, Environmental Pollutants, Sensitivity and Specificity, Chromatography, High Pressure Liquid, Drug Residues, Food Analysis
Spectrometry, Mass, Electrospray Ionization, Explosive Agents, Proteome, Plant Extracts, Pesticide Residues, Reproducibility of Results, Environmental Pollutants, Sensitivity and Specificity, Chromatography, High Pressure Liquid, Drug Residues, Food Analysis
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