AbstractThe poem below presents a brief review of amino acid abbreviations and structures. Among the featured facts are the following: histidine has a pKa close to the normal pH of the cytosol and therefore is an effective intracellular buffer, the R group of isoleucine is hydrophobic, and many protein kinases add a phosphate at the ‐OH site of tyrosine.This work is just one of many science songs and poems that may be used for educational purposes. A comprehensive database of over 2,000 songs is available online at www.science‐groove.org/MASSIVE/.