Vortex chamber for in situ recovery of the antibiotic myxovirescin A in continuous cultivation

descriptionPublicationkeyboard_double_arrow_right Article 05 Feb 1987 English Publisher:WileyJournal:Biotechnology and Bioengineering, volume 29, pages 222-227 (issn: 0006-3592, eissn: 1097-0290,

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Authors: V, Hecht; J, Vorlop; H, Kalbitz; K, Gerth; J, Lehmann;

doi: 10.1002/bit.260290212

pmid: 18576379

Vortex chamber for in situ recovery of the antibiotic myxovirescin A in continuous cultivation

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Abstract

AbstractA vortex chamber for continuous adsorption of the antibiotic Myxovirescin A on XAD resins was developed. In this paper the design and use of the vortex chamber in an external bypass of a continuous process is described. Compared with the normal continuous process, the specific production rate of the antibiotic is four to five times higher when the antibiotic is continuously adsorbed. A semicontinuous process could be performed by using two chambers for adsorption and regeneration alternatively.

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