Model for oxygen transfer in a shake flask

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1978 English Publisher:WileyJournal:Biotechnology and Bioengineering, volume 20, pages 1,695-1,709 (issn: 0006-3592, eissn: 1097-0290,

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Authors: J. C. Van Suijdam; N. W. F. Kossen; A. C. Joha;

doi: 10.1002/bit.260201102

Model for oxygen transfer in a shake flask

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Abstract

AbstractThe shake flask is a very common and useful tool for the study of submerged fermentations on a small scale. However, the oxygen supply may easily become a limiting factor. A model for the aeration in shake flasks is presented that enables one to predict whether in the course of an experiment the oxygen supply is becoming a growth‐limiting factor or not. The results of measurements of the transfer coefficient of a cotton plug and the oxygen mass‐transfer coefficient kla are also given.

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Delft University of Technology
Netherlands

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