
doi: 10.1002/bit.21232
pmid: 17136749
AbstractComputer simulation offers unique possibilities for investigating molecular‐level phenomena difficult to probe experimentally. Drawing from a wealth of studies concerning protein folding, computational studies of protein aggregation are emerging. These studies have been successful in capturing aspects of aggregation known from experiment and are being used to refine experimental methods aimed at abating aggregation. Here we review molecular‐simulation studies of protein aggregation conducted in our laboratory. Specific attention is devoted to issues with implications for biotechnology. Biotechnol. Bioeng. 2007;96: 1–8. © 2006 Wiley Periodicals, Inc.
Protein Folding, Binding Sites, Protein Conformation, Sequence Analysis, Protein, Multiprotein Complexes, Proteins, Computer Simulation, Dimerization, Protein Binding
Protein Folding, Binding Sites, Protein Conformation, Sequence Analysis, Protein, Multiprotein Complexes, Proteins, Computer Simulation, Dimerization, Protein Binding
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