The unfolding mechanism of thermolysin

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983 English Publisher:WileyJournal:Biopolymers, volume 22, pages 101-105 (issn: 0006-3525, eissn: 1097-0282,

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Authors: R J, Corbett; R S, Roche;

doi: 10.1002/bip.360220116

pmid: 6673748

The unfolding mechanism of thermolysin

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Abstract

AbstractThe ligand‐modulated kinetics of the autoproteolysis of thermolysin and the high‐molecular‐weight products of the reaction provide evidence for the conclusion that separation of the two structural domains is most probably the first step on the unfolding pathway of the protein under native conditions.

Related Organizations

University of Calgary
Canada

Keywords

Kinetics, Protein Denaturation, Protein Conformation, Thermolysin, Bacillus, Calcium

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