
pmid: 24124082
AbstractGlycosylation is critical for the proper folding and function of many eukaryotic proteins. A lack of native asparagine‐linked glycosylation machinery has hampered production of eukaryotic proteins in Escherichia coli. This commentary by Danielle Tullman‐Ercek discusses the work of Matt Delisa's group on an assay using beta‐lactamase activity as a reporter for successful glycoprotein folding in the periplasm of E. coli.See accompanying article by Mansell et al. DOI: 10.1002/biot.201300026
Protein Folding, Protein Stability, Asparagine, Genetic Engineering, Glycoproteins
Protein Folding, Protein Stability, Asparagine, Genetic Engineering, Glycoproteins
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