Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao BioFactorsarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
BioFactors
Article . 2003 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
BioFactors
Article . 2004
versions View all 2 versions
addClaim

Thiols as major determinants of the total antioxidant capacity

Authors: A, Balcerczyk; A, Grzelak; A, Janaszewska; W, Jakubowski; S, Koziol; M, Marszalek; B, Rychlik; +3 Authors

Thiols as major determinants of the total antioxidant capacity

Abstract

The proper functioning of aerobic organisms subjected to the danger of uncontrolled oxidation depends critically on the efficient antioxidant system. This system includes antioxidant enzymes, low-molecular weight antioxidants and biological chelators of transition metal ions. What is an antioxidant? According to the apparently most useful definition, antioxidant is “any substance that, when present at low concentrations compared with those of an oxidizable substrate, significantly delays or prevents oxidation of that substrate” [1]. The usefulness of this definition lies, i. a., in its instrumentality as it suggests straightforward means of testing antioxidant properties of chemical compounds. In fact, testing the delay or inhibition of a chosen oxidation reaction allows for a simple measurement of the sum of all antioxidants present in the sample studied. This parameter is usually referred to as Total Antioxidant Activity or, as recommended lately, Total Antioxidant Capacity [2]. Total Antioxidant Capacity is an increasingly frequently measured parameter. While lacking detailed information about the composition and concentrations of individual antioxidant species present in a sample, it provides an easy and rapid means of evaluation of “antioxidant power” of the examined material. An obvious field of application of TAC assay is analysis of plants, food products and beverages. However, there are many attempts to apply this analysis for evaluation of antioxidant status of body fluids (especially blood plasma) in normal human subjects and animals. For research purposes, it is also of interest to evaluate TAC of cells and tissue homogenates in animals subjected to different treatments. There are numerous methods of estimating TAC. One group of methods is based on the inhibition of free-radical induced oxidation of an indicator compound or of a substrate yielding an indicator [3–5]. The

Keywords

Blood Proteins, Saccharomyces cerevisiae, Antioxidants, Uric Acid, Oxidative Stress, Animals, Humans, Benzothiazoles, Sulfhydryl Compounds, Sulfonic Acids, Oxidation-Reduction

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    45
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
45
Top 10%
Top 10%
Top 10%
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!