Affinity of polyphenols for lipid bilayers

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2000 English Publisher:WileyJournal:BioFactors, volume 13, pages 147-151 (issn: 0951-6433, eissn: 1872-8081,

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Authors: T, Nakayama; T, Hashimoto; K, Kajiya; S, Kumazawa;

doi: 10.1002/biof.5520130124

pmid: 11237174

Affinity of polyphenols for lipid bilayers

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Abstract

AbstractInteraction of tea catechins with lipid bilayers has been investigated with liposome systems. Epicatechin gallate had the highest affinity for lipid bilayers, followed by epigallocatechin gallate, epicatechin, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in the surface of lipid bilayer perturbed the membrane structure.

Related Organizations

University of Shizuoka
Japan
University of Shizuoka
Japan

Keywords

Flavonoids, Models, Molecular, Bacteria, Molecular Structure, Tea, Polymers, Lipid Bilayers, Molecular Conformation, Apoptosis, Catechin, Anti-Bacterial Agents, Structure-Activity Relationship, Phenols, Tumor Cells, Cultured, Animals, Anticarcinogenic Agents

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