Cyclins, cyclin‐dependent kinases and differentiation

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1997 English Publisher:WileyJournal:BioEssays, volume 19, pages 307-315 (issn: 0265-9247, eissn: 1521-1878,

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Authors: C Y, Gao; P S, Zelenka;

doi: 10.1002/bies.950190408

pmid: 9136628

Cyclins, cyclin‐dependent kinases and differentiation

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Abstract

AbstractCyclin‐dependent kinases and their regulatory subunits, the cyclins, are known to regulate progression through the cell cycle. Yet these same proteins are often expressed in non‐cycling, differentiated cells. This review surveys the available information about cyclins and cyclin‐dependent kinases in differentiated cells and explores the possibility that these proteins may have important functions that are independent of cell cycle regulation.

Related Organizations

National Institute of Health
Pakistan
National Eye Institute
United States
National Institutes of Health
United States

Keywords

Transcription, Genetic, Cyclins, Multigene Family, Animals, Gene Expression Regulation, Developmental, Apoptosis, Cell Differentiation, Saccharomyces cerevisiae, Models, Biological, Cyclin-Dependent Kinases

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