Retrovirus vectors and their uses in molecular biology

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1986 English Publisher:WileyJournal:BioEssays, volume 5, pages 252-257 (issn: 0265-9247, eissn: 1521-1878,

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Authors: E, Gilboa;

doi: 10.1002/bies.950050605

pmid: 3551938

pmc: PMC7161754

Retrovirus vectors and their uses in molecular biology

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Abstract

AbstractRetroviral vectors utilize the biochemical processes unique to retroviruses, to transfer genes with high efficiency into a wide variety of cell types in tissue culture and in living animals. With such vectors, the effect of newly introduced genes and the mechanism of gene expression can be studied in cell types so far refractory to other methods of transfer.

Related Organizations

Memorial Sloan Kettering Cancer Center
United States

Keywords

Retroviridae, Transduction, Genetic, DNA, Viral, Genetic Vectors, Animals, Hematopoietic Stem Cells

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