
doi: 10.1002/bies.10190
pmid: 12447981
Abstract The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype–phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications. BioEssays 24:1164–1177, 2002. © 2002 Wiley‐Periodicals, Inc.
Time Factors, Genotype, Temperature, Kinetics, Phenotype, Nucleic Acid Conformation, RNA, Thermodynamics, Neural Networks, Computer, Algorithms, Phylogeny
Time Factors, Genotype, Temperature, Kinetics, Phenotype, Nucleic Acid Conformation, RNA, Thermodynamics, Neural Networks, Computer, Algorithms, Phylogeny
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