
This report describes a case of severe limited Wegener's granulomatosis (WG) presenting in the third trimester of pregnancy with pansinusitis and necrotizing pneumonitis. The patient was treated successfully with a combination of corticosteroids and cyclophosphamide (CYC). The outcomes in the mother and the newborn were excellent. In a review of the English-language literature, we found 10 similar cases of WG with 13 pregnancies. WG occurring during pregnancy may have a more aggressive course and may require more aggressive treatment compared with WG occurring at other times. The treatment options for WG in pregnancy are discussed.
Adult, Pregnancy Complications, Pregnancy, Pregnancy Trimester, Third, Granulomatosis with Polyangiitis, Pregnancy Outcome, Humans, Female, Cyclophosphamide, Methylprednisolone
Adult, Pregnancy Complications, Pregnancy, Pregnancy Trimester, Third, Granulomatosis with Polyangiitis, Pregnancy Outcome, Humans, Female, Cyclophosphamide, Methylprednisolone
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