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Arthritis & Rheumatism
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Isolation of rheumatoid factors

Authors: Edith R. Schwartz; Ralph Heimer;

Isolation of rheumatoid factors

Abstract

AbstractA method for the separation of rheumatoid factors into two serologically distinct macroglobulins is described. Macroglobulins, reacting with cells coated with human as well as with rabbit gamma globulin, were found to be mainly 19.4S, but occasionally such preparations contained minor constituents sedimenting at 22s as well as 27s. Macroglobulins which reacted with cells coated with human gamma globulin, but which were inactive when rabbit gamma globulin was used, were mainly 19.5S. Some sera, however, contained substances serologically similar in behavior but sedimenting at 17.5S, 22.0S, and 27s.

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Keywords

Arthritis, Rheumatoid, Rheumatoid Factor, Arthritis, Serum Globulins

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    Average
    influence
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
34
Average
Top 10%
Top 10%
bronze
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