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Arthritis & Rheumatism
Article . 1960 . Peer-reviewed
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Examination of the latex fixation test using sulfated mucopolysaccharides

Authors: R, HEIMER; R H, FREYBERG;

Examination of the latex fixation test using sulfated mucopolysaccharides

Abstract

AbstractThe sulfated mucopolysaccharides heparin and chondroitin sulfate are immunologically inactive toward highly purified rheumatoid factors or any other components of the serum of individuals with rheumatoid arthritis. Positive latex fixation tests of selected serum samples using heparin in place of human gamma globulin are due to the simultaneous presence of endogenous gamma globulin. Nearly similar results may he obtained with latex tests using no coating agent whatever. Addition of heparin to latex suspensions imparts stability to the colloidal dispersion and remedies prozone phenomena encountered in such titrations.

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Keywords

Humans, Latex Fixation Tests, Glycosaminoglycans

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    popularity
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    influence
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Top 10%
Top 10%
bronze
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