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pmid: 27000559
pmc: PMC5071768
AbstractFinding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health. The past decades have seen a dramatic worldwide increase in human‐pathogenic bacteria that are resistant to one or multiple antibiotics. More and more infections caused by resistant microorganisms fail to respond to conventional treatment, and in some cases, even last‐resort antibiotics have lost their power. In addition, industry pipelines for the development of novel antibiotics have run dry over the past decades. A recent world health day by the World Health Organization titled “Combat drug resistance: no action today means no cure tomorrow” triggered an increase in research activity, and several promising strategies have been developed to restore treatment options against infections by resistant bacterial pathogens.
Bacteria, Antibiotic resistance, Reviews, Medicinal chemistry, Molecular Dynamics Simulation, Organophosphates, Drug design, Anti-Bacterial Agents, 540: Chemie, Structure-Activity Relationship, 615: Pharmakologie und Therapeutik, Bacterial Proteins, Drug Design, Drug Resistance, Multiple, Bacterial, Macrolides, Oxazoles, Oxazolidinones
Bacteria, Antibiotic resistance, Reviews, Medicinal chemistry, Molecular Dynamics Simulation, Organophosphates, Drug design, Anti-Bacterial Agents, 540: Chemie, Structure-Activity Relationship, 615: Pharmakologie und Therapeutik, Bacterial Proteins, Drug Design, Drug Resistance, Multiple, Bacterial, Macrolides, Oxazoles, Oxazolidinones
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 401 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 0.1% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 1% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 0.1% |