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Genotyping—From Genomic DNA to Genotype in a Single Tube

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 08 Dec 2005 Germany Publisher:WileyJournal:Angewandte Chemie International Edition, volume 44, pages 7,842-7,849 (issn: 1433-7851, eissn: 1521-3773,

Authors: Strerath, Michael; Marx, Andreas;

doi: 10.1002/anie.200501444 , 10.1002/chin.200609278

pmid: 16231379

Genotyping—From Genomic DNA to Genotype in a Single Tube

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Abstract

AbstractNucleotide variations in the human genome, such as single‐nucleotide polymorphisms, have been researched more intensively since it became apparent that these deviations are linked to various diseases and also several side effects of drugs. The investigation of genomic DNA in the laboratory requires routine methods that are time‐, labour‐, and cost‐effective. These criteria are fulfilled by so‐called closed‐tube methods, which are applied directly to isolated genomic DNA without any preamplification.

Country

Germany

Related Organizations

University of Konstanz
Germany

Keywords

Genome, Time Factors, info:eu-repo/classification/ddc/540, Genotype, Cytogenetic Analysis, Humans, DNA, Polymorphism, Single Nucleotide

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	75
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%