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International Forum of Allergy & Rhinology
Article . 2025 . Peer-reviewed
License: CC BY NC
Data sources: Crossref
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PubMed Central
Article . 2025
License: CC BY NC
Data sources: PubMed Central
International Forum of Allergy & Rhinology
Article . 2026
Data sources: Europe PubMed Central
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Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis

descriptionPublicationkeyboard_double_arrow_right Article 29 Nov 2025 English Publisher:WileyJournal:International Forum of Allergy & Rhinology, volume 16, pages 110-113 (issn: 2042-6976, eissn: 2042-6984, Copyright policy )
Authors: Jacquelyn K. Callander; Annabelle R. Charbit; Camryn Marshall; Kritika Khanna; Steven D. Pletcher; Jose G. Gurrola; Andrew H. Murr; +3 Authors

doi: 10.1002/alr.70076

pmid: 41317131

pmc: PMC12761348

Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis

Abstract

Key Points Eosinophil peroxidase (EPX) correlates with local type 2 inflammation and may serve as a noninvasive biomarker of eosinophilic chronic rhinosinusitis. EPX declines after surgery and dupilumab, highlighting its potential to track treatment response. High baseline EPX predicts patients likely to achieve a clinically meaningful Sinonasal Outcome Test‐22 change.

Related Organizations
Keywords

Eosinophils, Male, Research Note, Eosinophil Peroxidase, Treatment Outcome, Rhinosinusitis, Chronic Disease, Eosinophilia, Humans, Sinusitis, Antibodies, Monoclonal, Humanized, Biomarkers, Rhinitis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
hybrid