
pmid: 25866154
In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.
Neurologi, Electrical Equipment and Supplies, Action Potentials, Electrons, Neuroengineering, Tissue Culture Techniques, PSS [PEDOT], Mice, PEDOT:PSS, Animals, Magnesium, CA1 Region, Hippocampal, gamma-Aminobutyric Acid, Ions, Epilepsy, Pyramidal Cells, Organic Electronic Ion Pump, Equipment Design, CA3 Region, Hippocampal, Organic Bioelectronics, Neurology, Chlorates, Anticonvulsants
Neurologi, Electrical Equipment and Supplies, Action Potentials, Electrons, Neuroengineering, Tissue Culture Techniques, PSS [PEDOT], Mice, PEDOT:PSS, Animals, Magnesium, CA1 Region, Hippocampal, gamma-Aminobutyric Acid, Ions, Epilepsy, Pyramidal Cells, Organic Electronic Ion Pump, Equipment Design, CA3 Region, Hippocampal, Organic Bioelectronics, Neurology, Chlorates, Anticonvulsants
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 1% |
