The topic of sustainability is crucial for the wellbeing of populations and of their future generations but is complex to address. It can be analysed from several perspectives, as those of policymakers, companies and even individuals willing to undertake appropriate actions in this regard. Focusing on the enterprises, such a complexity is made even higher due to the numerous processes that can affect the sustainability of an organisation and to the wide range of choices to be made in each of them. The perimeter of investigation of this book refers to operations and supply chain management processes carried out within companies, with the aim of identifying the principles, frameworks and managerial tools that can be adopted along the life cycle of the product to achieve a satisfactory overall performance, in accordance with the triple bottom line approach.