descriptionPublicationkeyboard_double_arrow_right Article 21 Jun 1971 English Publisher:American Medical Association (AMA)Journal:JAMA: The Journal of the American Medical Association, volume 216, page 2,011 (issn: 0098-7484,

Authors: Burton Sack; David S. Rosenthal;

doi: 10.1001/jama.1971.03180380065019

pmid: 5108636

Autoimmune Hemolytic Anemia in Scleroderma

- Summary
- Subjects
- Metrics

Abstract

In a case of scleroderma and autoimmune hemolytic anemia, azathioprine treatment resulted in complete remission of the hemolysis despite the persistence of positive direct and indirect antiglobulin test. There were no beneficial results of the therapy on the underlying connective tissue disorder. Complications of azathioprine treatment encountered were completely reversed with termination of therapy. These concurrences, with the positive antinuclear antibody studies and rheumatoid factor, favor the autoimmune theory of pathogenesis of scleroderma.

Keywords

Male, Scleroderma, Systemic, Remission, Spontaneous, Clinical Enzyme Tests, Middle Aged, Coombs Test, Hematocrit, Liver Function Tests, Adrenal Cortex Hormones, Azathioprine, Humans, Anemia, Hemolytic, Autoimmune

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	25
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average