Two hundred thirty-one female patients of private obstetricians and gynecologists were examined for gonorrhea, using cultural techniques. Specimens were taken from the cervix and rectum of all patients and cultured on Thayer-Martin (TM) selective medium. Six, or 2.6%, were found positive. Of these, all were in the 20- to 29-year age group; only one had knowledge of being exposed to gonorrhea; three were pregnant. The frequently asymptomatic nature of gonorrhea in females, combined with a definable incidence of infection in this patient group, suggests that more frequent use of cultural methods employing TM medium would help control this rapidly increasing disease. Cultures are particularly recommended for women under 30 years who are single, pregnant, or manifest acute vaginitis.