Pellagra was first described by Gasper Casal in 1750, under the name of"mal de la rosa,"and since then has been found to be prevalent in many countries. It is said that there were fully 100,000 cases in Italy in 1905, and at least 3,000 of these were in the lunatic asylums. Many cases have been reported from the various tropical and subtropical countries, but none from the United States until 1907; although in 1902, Dr. H. F. Harris reported to the Georgia Medical Association a case of ankylostomiasis with pellagrous symptoms and called attention to the possibility of this disease being present in Georgia. In July, 1907, Dr. George H. Searcy1reported an epidemic of acute pellagra at the Mount Vernon Hospital for the (colored) Insane in Alabama. Dr. J. W. Babcock2of the State Hospital for the Insane at Columbia, S. C., made in December, 1907,